Toxicological Study of Ocimum sanctum Linn Leaves: Hematological, Biochemical, and Histopathological Studies / M. K. Gautam and R. K. Goel / Journal of Toxicology, Volume 2014 (2014) / http://dx.doi.org/10.1155/2014/135654 Co-administration with indomethacin marginally improved the anti-inflammatory activity. • Anti-Fertility / Abortifacient: Leaves of O sanctum are said to be abortifacient in women. Vol. 24 Issue (3): 156-163 / DOI: 10.5246/jcps.2015.03.019 (31) (HOLY BASIL): PHARMACOLOGY BEHIND ITS ANTI- CANCEROUS EFFECT / BABY JOSEPH AND VRUNDHA M. NAIR* / Int J Pharm Bio Sci 2013 Apr; 4(2): (P) 556 - 575 (61) (27) Usage Frequency: 1 through a central nervous system pathway that may involve the GABA-ergic may be promising for human radiation protection. Results showed the basil essential oils, especially the O. sanctum oil, have anxiolytic and antidepressant effects, and might have alternative or complementary potential in the prevention or treatment of conditions related to AD. Effects of drying, fermented and unfermented tea of Ocimum tenuiflorum Linn. Effect of ethanolic leaf extract of Ocimum sanctum on haloperidol-induced evaluation of hypoglycaemic activity of some Indian medicinal plants 2010 Oct-Dec; 1(4): 208–210. DRUGS IN RATS, THERAPEUTIC USES OF OCIMUM SANCTUM LINN (TULSI) WITH A NOTE ON EUGENOL AND ITS PHARMACOLOGICAL ACTIONS: A SHORT REVIEW, Evaluation of cardioprotective activity of Ginkgo biloba and Ocimum sanctum in rodents, Effect of ethanolic leaf extract of Ocimum sanctum on haloperidol-induced catalepsy in albino mice, Effect of O. sanctum Linn on normal and dexamethasone suppressed wound healing, Immunomodulatory activity of aqueous extract of Ocimum sanctum in rat, Ocimum sanctum leaf extracts stimulate insulin secretion from perfused pancreas, isolated islets and clonal pancreatic β-cells, Thrombolytic potential of O. sanctum, C. longa, Azadirachta indica and Anacardium occidentale, Study of Antibacterial Activity of Ocimum sanctum Extract Against Gram Positive and Gram Negative Bacteria, PRELIMINARY EVALUATION OF OCIMUM SANCTUM AS TOXICANT AND REPELLENT AGAINST TERMITE, HETEROTERMES INDICOLA (WASMANN) (ISOPTERA: RHINOTERMITIDAE), Effect of tulsi (Ocimum Sanctum Linn.) It has a … MyMemory is the world's largest Translation Memory. basil translation in English-Tagalog dictionary. • Thrombolytic Potential: Study evaluated four aqueous herbal extracts viz., O. sanctum, C. longa, A. indica and A. occidentale. opioid and GABA-ergic system. Study shows an antitussive effect probably by central action mediated through both ; Diabetes.Some early research suggests that a holy basil leaf extract might decrease blood sugar in people with type 2 diabetes. Antibacterial necrosis: a haemodynamic, biochemical and histoarchitectural assessment / D. S. Arya, M. Nandave, S. K. Ojha, S. Kumari, Results suggest a potential use as a male contraceptive agent. Bhutani / Proc. - Seed decoction used as demulcent. (36) (3) Ocimum tenuiflorum is sharp and peppery, with perhaps a touch of lemon.. Quality: This list does not contain fictional plants such as aglaophotis, or recreational drugs such as tobacco.. Usage Frequency: 2 • Antibacterial Synergism: Study evaluated the in vitro antibacterial activity of O. sanctum against bacterial strains associated with infectious diseases i.e., Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. Usage Frequency: 44 • Toxicological Study / Leaves: Study of 50% ethanol extract of Ocimum sanctum leaves were evaluated for acute and subacute toxicity. C. Franz, Á. (15) DRUGS IN RATS / IInndiaann JJ PPhhyysisoilo Pl hPahramramcoalc 4, No. (39) Last Update ... holy basil. Results showed stimulation of insulin secretion from perfused rat pancreas, isolated rat islets, and clonal rat ß-cell line in a concentration dependent manner. An Experimental Study of Analgesic Effect of Medicinal Plant Tulsi (Ocimum sanctum) / Reema Rathore and Shashi Jain / Ethno Med, 7(1): 27-30 (2013) • Immunoregulatory: Study in albino rats of a methanol extract and aqueous suspension of leaves for its immunoregulatory profile to antigenic challenge to Salmonella typhosa and sheep erythrocyte agglutination tests showed immunostimulation of humoral immunologic response shown by an increase in antibody titer as well as a cellular immunologic response. (23) Quality: • Antioxidant: Study suggested a potential for a breast cancer preventive and therapeutic agent. • Clinical Efficacy and Safety of Tulsi in Humans / Review: This comprehensive literature review reports on the clinical outcome after ingestion of tulsi. 5, No. and Na 0.74%. An example of a PAH is benzo[a]pyrene, with toxicity that results from bioactivation of B[a]P to diolepoxides by monooygenase enzymes. App. (14) Sci, 2014; 3(1): pp 198-205 You can boil 5-6 fresh tulsi leaves can be boiled in water for ten minutes and then steeped as hot tea. isolated islets and clonal pancreatic ß-cells, EFFECT OF ISP-induced myocardial necrosis probably through improved ventricular Solasi is a common name shared by (1) Luminitzera racemosa, Kulasi, and (2) Ocimum basilicum, solasi, and and phonetically with (3) Ocimum sanctum, sulasi. important mode of its hepatoprotective effect. on sperm count and reproductive hormones in male albino rabbits, Efficacy of an Extract of Ocimum tenuiflorum (OciBest) in the Management of General Stress: A Double-Blind, Placebo-Controlled Study, Effects of drying, fermented and unfermented tea of Ocimum tenuiflorum Linn. There three separate listing of medicinal plants: a Tagalog list, an English list for those plants with English designations, and a Chinese list, for the medicinal plants with Chinese names. (see study below) (36) Posological report clearly showed that Ayurvedic uses of O. sanctum are in doses significantly lower than the dose at which antifertiity effects were observed. (7) Monk's basil (Engl.) Ocimum sanctum Linn. Find more Filipino words at wordhippo.com! (37) Quality: (45) Holy Basil leaf extract decreases tumorigenicity and metastasis of aggressive human pancreatic cancer cells in vitro and in vivo: potential role in therapy. Godhwani, D.S. (55) TELUGU: Brynda, Gaggera, Krishnatulsi, Kukka pala, Oddhi , Tulasi, Tulsi, Tulsichettu. Results suggest its potential use in the prevention of drug-induced extrapyramidal side effects. These compounds are inhibited by active compounds extracted from Black tulsi viz., eugenol, carvacrol, elemene, caryophyllene and linalool. Reference: Wikipedia, Last Update: 2015-06-10 Quality: 4: Targeted Screening of MAPs, Economics & Law Eds. OT showed anticancer activity against MCF-7 (a hormone-dependent breast cancer cell line). (49). MALAY: Kemangi, Selasih merah, Selasih Siam. from the leaves of OS were studied by evaluating chromosome aberration MALAYALAM: Krishnatulasi, Kunnakam, Punya, Shivatulasi, Shri tulasi, Sivatulasi, Trittavu, Tulasi. Quality: Reference: Anonymous, Last Update: 2018-07-03 (12) Ocimum tenuiflorum Linn. • Hepatoprotective / Carbon Tetrachloride Toxicity: Study of an aqueous extract of Ocimum sanctum showed hepatoprotective activity in carbon tetrachloride induced toxicity in albino rats. English-Tagalog Online Translator Write Word or Sentence (max 1,000 chars): English to Tagalog. Reference: Anonymous, Last Update: 2020-09-28 Mineral analysis showed N 3.30%, P 1.10%, K 6.62%, S 1.55%. (34) (21) Extract of fresh leaves of O. sanctum exhibited an alteration in humoral immunoresponse in experimental model on albino rats. The interaction necessitates dose readjustment of Glimepiride and frequent monitoring of glucose levels. (32) • Posological Considerations per Ayurvedic Pharmaceutical Science: A 2010 study reported that the administration of 2 g of O. sanctum leaves for 30 days in male albino mice showed adverse effect on sperm count and male hormones. Crude extracts showed lower IC50 (<100 µg/ml) against cancer cell lines without effect of HS-27. (50) Craker and Z.E. Attenuation of Hydrogen Peroxide Induced Cytotoxic changes in Human Lens Epithelial Cells / Leaves: Hydrogen peroxide (h2O2) is a major oxidant involved in cataract formation. Reference: Wikipedia, Last Update: 2013-11-23 In theory, holy basil might worsen hypothyroidism. The immunostimulant capability was attributed to the plants adaptogenic action. Effect of ethanolic leaf extract of Ocimum sanctum on haloperidol-induced catalepsy in albino mice / S Pemminati, V Nair et al / Indian Jour of Pharmacology, 2007, Vol 39, Issue 2, Pp 87-89. THAI: Ka phrao, Ka phrao daeng khon, Ka phrao khon, Kom ko dong, Tu thai. mice with sarcomatous tumor resulted in a significant reduction in tumor (57 • Chemical Composition / Antioxidant / Antimicrobial / Leaves: Study of leaves for antimicrobial activity showed E. coli and E. faecalis were highly susceptible to methanol extract. • Anti-Stress: A randomized, double-blind, placebo controlled study evaluated the efficacy of OciBest, an extract of Ocimum tenuiflorum in symptomatic control of general stress. Immunomodulatory activity of aqueous extract of Ocimum sanctum in rat / R. Caroline Jeba et. free radical scavenging effect and attributes the antioxidant property • Anti-Tussive: Maximum repellency was seen in the methanol root extracts while water extracts showed minimum repellency. Ocimum sanctum— A preliminary study evaluating its immunoregulatory profile in albino rats / Savitri Godhwani, J.L. Results showed OciBest (whole plant extract) to be 1.6 times or 39% more effective in the management of stress symptoms compared to placebo and was well tolerated by all patients over a six-week period study. The antidiabetic effect observed with the combination of the aqueous extract and glimepiride was significant and more when compared to either drug alone. (21) • Antibacterial: (57) (52) may be used to prevent drug-induced extrapyramidal effects. Also known as Tulsi, Holy Basil boasts long, green, jagged-edge leaves with purple stems. $9.63 $ 9. Results showed a significant decrease in sperm count with marked increase in serum testosterone and significant reductions in FSH and LH. foods. sanctum Linn--a study on gastric ulceration and gastric secretion in • Antihelmintic: Essential oil of Ocimum sanctum and its dominant component, eugenol, tested inn vitro, exhibited potent anthelmintic activity in the Caenorhabditis elegans model. (54) Antiulcerogenic property was also studied in pyloric-ligated and aspirin-treated rats. necrosis: a haemodynamic, biochemical and histoarchitectural assessment, Anticancer 284-288 Called Tulsi or Sacred basil in its native India and used for religious purposes, Holy basil is revered and is not typically used for cooking. OS essential oil showed marked antibacterial efficiency against all milk secretion. Holy basil is related to the familiar sweet basil that's used in cooking. English: Holy Basil Latin: Ocimum sanctum (“sacred fragrant lipped basil”) or Ocimum tenuiflorum (“basil with small flowers”) or Ocumum gratissimum (“very grateful basil”) Botanical Family: Lamiaceae (mint) Hindi: Tulsi Sanskrit: Tulasi. (43) OS extract did not produce any hazardous symptoms or death and CNS or ANS effects in acute toxicity test. The reviewed studies reinforce traditional uses and suggests tulsi is effective for the treatment of lifestyle-related chronic diseases including diabetes, metabolic syndrome, and psychological stress. / doi: 10.4103/0974-7788.76782 Reference: Wikipedia, Last Update: 2016-10-27 Study showed Ocimum sanctum has a protective effect against haloperidol-induced catalepsy. 37, No. Parts utilized Findings suggest that the leaf extracts have a stimulatory effect on the physiological pathways of insulin secretion. Chronic toxicity studies of aqueous leaf extract of Indian traditional medicinal plant Ocimum tenuiflorum (Linn.) (8) Evaluation of phyto constituent and synergistic antibacterial activity of Ocimum sanctum extract against some gram-positive and gram-negative species / Fatema Shah, Ziaul Hasan and Kamal Uddin Zaidi / Biosci. Mohd Fasih Ahmad, Raj K. Keservani*, D J Mani Babu / Journal of Chinese Pharmaceutical Sciences 2015, Vol. Reference: Anonymous, Last Update: 2015-05-01 Oil of leaves yielded comparable amount of antioxidant as ascorbic acid, flavonoid and total phenol as well as linolenic acid, polyunsaturated fatty acid. dahon ng basil sa bicol. (2) Queen of herbs (Engl.) • Eugenol / Aerial Parts: Ocimum sanctum is a cheaper source for the commercial extraction of eugenol. Subacute testing did not show any changes in body weight, food and water consumption, hematological and biochemical profiles. are oblong-ovate and 2 to 4.5 centimeters long, with pointed or blunt tips, and somewhat It promotes health and wellbeing and protects the mind and body in a very positive way. Bull., 2014; 2(6): pp 609-611 / DOI: 10.17628/ECB.2014.3.609 on the antioxidant capacity / Rabeta, M.S. ; Stress.In early research, taking 400 mg of a holy basil extract (M/s … Results showed significant alteration in general behavioral pattern by Water Maze Test and potentiation of pentobarbitone induced hypnosis in mice. 2(1), 2011, 33-38 Green synthesis of silver nanoparticles using Ocimum sanctum (Tulashi) and study of their antibacterial and antifungal activities / Yogeswari Rout , Sikha Behera, Akshya Kumar Ojha and P. L. Nayak* / Journal of Microbiology and Antimicrobials Vol. Anticancer Results showed O. tenuiflorum to act as a good inhibitor for corrosion of steel in 1M Hcl. comparative study of radioprotection by Ocimum flavonoids and synthetic Skin infection: Holy basil contains multiple compounds with antibacterial properties that may help the body fight infections. (see constituents above) (46) in bone marrow cells of irradiated mice. Reduction of edema by O. sanctum was better than indomethacin. (7) - Dried plant in decoction used for croup, diarrhea, catarrh, bronchitis and diarrhea. - In Malaya, juice used externally in an imbrocation for rheumatism. (26) AGAINST LEAD INDUCED TOXICITY IN ALBINO RATS, Anthelmintic Activity of Tulsi Leaves (Ocimum Sanctum Linn)–An In-Vitro Comparative Study, ANTI-INFLAMMATORY ACTIVITY OF EXTRACTED EUGENOL FROM OCIMUM SANCTUM L. LEAVES, Evaluation of Some Chemical Composition, Minerals Fatty Acid Profiles, antioxidant and Antimicrobial Activities of Tulsi (Ocimum sanctum) from India, Rationale for Immunomodulatory and Anti-inflammatory Effects of Ocimum sanctum: Radical Scavenging Potential and Effect on Nitric Oxide Production, Chronic toxicity studies of aqueous leaf extract of Indian traditional medicinal plant Ocimum tenuiflorum (Linn.) Results showed significant analgesic activity (p<0.01) in all three test doses, with better efficiency seen at higher concentration. (4) Results showed significant clot lysis compared with vehicle control. of Philippine Medicinal Plants with Chinese Names. OCIMUM SANCTUM (OS) LEAF EXTRACT ON HEPATOTOXICITY INDUCED BY ANTITUBERCULAR • Antifungal / Leaves: Study evaluated an aqueous leaf extract against four common species of fungi viz., A. niger, Rizopous, Cladpsporium and Curvularia lunata isolated from archeological sites. Studies 1 March, 2011) / International Journal on Pharmaceutical and Biomedical Research (IJPBR)Vol. The benzene and petroleum ether extracts of leaves have been reported to produce 80% to 60% antifertility activity in female rats. (24) The activity may be via reduction of H2O2 through its antioxidant property, supporting the concept that the extracts can penetrate HLEC membrane. Inhibition of breast cancer progression by a medicinal herb Ocimum sanctum / Pratima Nangia-Makker,  Larry Tait, Victor Hogan, Fred Miller and Avraham Raz / Proc Amer Assoc Cancer Res, Volume 47, 2006 Human translations with examples: tulsi, kumin, banal, balanoy, kamangkaw, diyos ko!, mahal kita, santa sede. Reference: Anonymous. Snow Barlow / Maintained by: Michel H. Porcher / MULTILINGUAL MULTISCRIPT PLANT NAME DATABASE / Copyright © 1997 - 2000 The University of Melbourne. Usage Frequency: 1 (18) Anthelmintic Activity of Tulsi Leaves (Ocimum Sanctum Linn)–An In-Vitro Comparative Study / Madhavulu Buchineni*, Rama Mohan Pathapati, Jithendra Kandati / Saudi J. Med. Leaves - Decoction of roots and leaves used for gonorrhea; externally used for rheumatic pains and paralysis. Calyx at the time of flowering is about 3 millimeters long and somewhat larger in fruit; the two lower teeth are long-awned, the upper one broadly-oblong, and the lateral ones very broad. 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