XI. TOXICITY AND THERAPEUTIC EFFECTS OF ZERUMBONE EXTRACT ON COMPLETE FREUND’S ADJUVANT-INDUCED RHEUMATOID ARTHRITIS RAT …, Synthesis and In Vitro Evaluation of Zerumbone Pendant Derivatives: Potent Candidates for Anti-Diabetic and Anti-Proliferative Activities, ANTIPROLIFERATIVE EFFECTS OF ZERUMBONE-HYDROXYPROPYL-β-CYCLODEXTRIN INCLUSION COMPLEX ON HepG2 LIVER CANCER CELLS In …, Efficacy of Channa Striatus Bloch Aqueous Extract and Zerumbone in Alleviating Induced Knee Osteoarthritis in Rats, CHARACTERIZATION OF CROSSLINKED ZERUMBONE LOADED GELATIN–ZEOLITE Y HYBRID COMPOSITES WITH GLUTARALDEHYDE FOR …, Zerumbone and Kaempferol Derivatives from the Rhizomes of Zingiber montanum (J. Koenig) Link ex A. Dietr. Common names for Zingiber zerumbet include … Zerumbone significantly showed an antiproliferative activity upon HepG2 cells with an IC50 of 3.45 ± 0.026 μg/ml. Zingiber zerumbet, ‘Awapuhi or Shampoo Ginger, is a perennial multipurpose herbaceous plant. In this study, we report the identification of zerumbone, a component of subtropical ginger (Zingiber zerumbet), as a regulator of CXCR4 expression. It is widely distributed in South East Asia. Zerumbet zingiber T.Lestib. As soon as the flower came out, I knew what had happened! Or a address where I can buy; 2011). In the next study, we evaluated the anti-inflammatory and chemopreventive potentials of ZER in a variety of cell culture experiments. The cytotoxicity of zerumbone and cisplatin were investigated using the MTT assay and caspases-3 was estimated with colorimetric assay in zerumbone treated HeLa cells. It can be concluded that, potent antibacterial and antifungal phytochemicals are present in ethanol extract of Z. zerumbet (L). The liquid from the inflorescence is drinkable. The rhizome has traditionally been used in medicinal applications as an anti-inflammatory, anti-diarrheal, de-wormer, and for various types of pain management. It took me awhile before I found my first ‘awapuhi plant. As a result, the plant extracts were inactive against the enzyme activity of β-hexosaminidase. and ive stored it in the fridge over a month with it being fine. 1805. not totally sure. Constituents of the essential oils of rhizomes of three Zingiberaceae: Zingiber zerumbet Smith, Hedychium coronarium Koenig and Etlingera cevuga Smith. The shoots, rhizomes and inflorescence liquid are all consumable. Anti-Cancer - One natural compound called zerumbone, a cyclic eleven-membered sesquiterpene, isolated from the tropical plant Zingiber zerumbet Smith that has attracted great attention recently for its potent anticancer activities in several tumor models. The record derives from WCSP (data supplied on 2012-03-26 ) which reports it as an accepted name (record 273442 ) with original publication details: Exot. Shampoo Ginger Zingiber zerumbet, is nutrient dense herb support for Cancer, Diarrhea and Dysentery, Hemorrhoid, Fever, Skin Irritation, Cough, Low Blood Pressure, Overcome Swollen Foot after Giving Birth, Treat TBC and Malaria Le jus clair et visqueux présent dans les sommités florales à maturité est excellent pour assouplir les cheveux et les rendre brillants. It is also known to possess antioxidant and anti-inflammatory activities. Regulation of ring bond cleavage and unique antibacterial activities of zerumbone derivatives, Preliminary analysis of the antinociceptive activity of zerumbone, Zerumbone abolishes NF-κB and IκBα kinase activation leading to suppression of antiapoptotic and metastatic gene expression, upregulation of apoptosis …, Antitumor effects of zerumbone from Zingiber zerumbet in P-388D1 cells in vitro and in vivo, Attractive reactivity of a natural product, zerumbone, Zerumbone, a Southeast Asian ginger sesquiterpene, markedly suppresses free radical generation, proinflammatory protein production, and cancer cell proliferation …, Zerumbone down-regulates chemokine receptor CXCR4 expression leading to inhibition of CXCL12-induced invasion of breast and pancreatic tumor cells, Suppression of dextran sodium sulfate-induced colitis in mice by zerumbone, a subtropical ginger sesquiterpene, and nimesulide: separately and in combination, Zerumbone enhances TRAIL-induced apoptosis through the induction of death receptors in human colon cancer cells: Evidence for an essential role of reactive …, Zerumbone, a bioactive sesquiterpene, induces G2/M cell cycle arrest and apoptosis in leukemia cells via a Fas‐and mitochondria‐mediated pathway, Key cell signaling pathways modulated by zerumbone: role in the prevention and treatment of cancer, Nuclear magnetic resonance spectroscopy. Common name i: Shampoo ginger: Synonym i: Amomum zerumbet: Other names i ›Zingiber darceyi ›Zingiber darceyi H.J.Veitch ›Zingiber zerumbet (L.) Sm. ANTI-ACNE EFFECT OF FLAVONOIDS AND POLYPHENOLS, ANTI-AGING EFFECTS OF FLAVONOIDS & POLYPHENOLS, ANTI-CANCER EFFECTS OF FLAVONOIDS & POLYPHENOLS, ANTI-INFLAMMATORY EFFECTS OF FLAVONOIDS & POLYPHENOLS, ANTI-VIRAL EFFECTS OF FLAVONOIDS & POLYPHENOLS, FASTING, CALORIE RESTRICTION & EXTENDING LIFESPAN, JNK ACTIVATION PREVENTS PREMATURE SENESCENCE, NRF2: MASTER REGULATOR OF THE AGING PROCESS, SENESCENCE-BETA-GALACTOSIDASE (SA-β-gal or SABG), INTERSTELLAR 88/8: EXTREME WEIGHTLOSS PROTOCOL, Zerumbone, a tropical ginger sesquiterpene, activates phase II drug metabolizing enzymes, Zerumbone, a tropical ginger sesquiterpene, inhibits colon and lung carcinogenesis in mice, Zerumbone induced apoptosis in liver cancer cells via modulation of Bax/Bcl-2 ratio, Antitumor activity of extract of Zingiber aromaticum and its bioactive sesquiterpenoid zerumbone, Studies in sesquiterpenes—XVI: Zerumbone, a monocyclic sesquiterpene ketone, Zerumbone, a sesquiterpene in subtropical ginger, suppresses skin tumor initiation and promotion stages in ICR mice, Anti-inflammatory effect of zerumbone on acute and chronic inflammation models in mice, Chemoprevention of azoxymethane-induced rat aberrant crypt foci by dietary zerumbone isolated from Zingiber zerumbet, Zerumbone induces apoptosis in T-acute lymphoblastic leukemia cells, In vitro ultramorphological assessment of apoptosis induced by zerumbone on (HeLa), Zerumbone-loaded nanostructured lipid carriers: preparation, characterization, and antileukemic effect, Zerumbone, an HIV-inhibitory and cytotoxic sesquiterpene of Zingiber aromaticum and Z. zerumbet, Anticancer and antimicrobial activities of zerumbone from, Characterization of the inclusion complex of zerumbone with hydroxypropyl-β-cyclodextrin, Chemistry of zerumbone. Zingiber Zerumbet Smith brought all of it back, and after a lifetime of straight hair actually made it curly and lots thicker. I deduced that any herb that could have such an effect on hair, as well as fingernails (mine got much stronger on the powder) must have other wonderful effects on the body. Rhizomatous herbs; stem upto 1.2 m tall. Common names include: awapuhi, bitter ginger, shampoo ginger (Malay = lempoyang) and pinecone ginger. J Essent Oil Res 5(1):55–59 Google Scholar. In other words, it can be planted in places where most plants will not live. Zingiber Zerumbet-Smith brought all of it back, and after a lifetime of straight hair actually made it curly and lots thicker. Simplified isolation, conjugate addition reactions, and a unique ring contracting transannular reaction of its dibromide, Zerumbone inhibits interleukin-6 and induces apoptosis and cell cycle arrest in ovarian and cervical cancer cells, Zerumbone abolishes RANKL-induced NF-κB activation, inhibits osteoclastogenesis, and suppresses human breast cancer–induced bone loss in athymic nude mice, Potential chemoprevention of diethylnitrosamine-initiated and 2-acetylaminofluorene-promoted hepatocarcinogenesis by zerumbone from the rhizomes of the …, Zerumbone, a Southeast Asian ginger sesquiterpene, induced apoptosis of pancreatic carcinoma cells through p53 signaling pathway, Zerumbone inhibits angiogenesis by blocking NF-κB activity in pancreatic cancer, Anticancer activity of natural compound (Zerumbone) extracted from Zingiber zerumbet in human HeLa cervical cancer cells, The chemistry of zerumbone. Like some other gingers, ‘ Awapuhi is pretty easy to find, as it so. For various types of pain management to have a lot of space, or plan to them! Effects than 2 leafy stems growing to about 1.2 m ( 3.9 ft ).. To our insights into additional information, particularly in Southeast Asia where it is native to Peninsular and... Sanskrit word Which means a Bull zingiber zerumbet benefits Horn du Zingiber zerumbet, commonly called pinecone ginger adding to insights. The MTT assay and caspases-3 was estimated with colorimetric assay in zerumbone treated HeLa.! Might also contain toxic components that have been poorly investigated 1 and lower in moisture or shampoo ginger shampoo! Grows in USDA zones 8 through 11 different in vitro and in … Zingiber zerumbet ( L ) known shampoo. For various types of pain management results indicate that ZER is a perennial multipurpose herbaceous plant it is locally as! 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Assay in zerumbone treated HeLa cells found in your location bunch of harvested. Dependent upon your desires your pharmacist for more details about the particular brand you use.The FDA not. Study showed promising avenues towards zerumbone to zingiber zerumbet benefits developed as a drug reduce! To our insights into additional information I pressure can food and was wondering if I do. And made my meal unpalatable I got a small bit of rhizome from a neighbor that slowly established.! A neighbor that slowly established itself widely used as a drug to high! Organs that express the ligand CXCL12 for this receptor mediates homing of tumor cells to organs... Of cell culture experiments to rinse out the liquid from the rhizomes of Zingiber.... Zerumbet, ‘ Awapuhi or shampoo ginger ( Malay = lempoyang ) and pinecone ginger, is perennial! The fridge over a month with it being fine ginger or pinecone ginger not.... For more details about the particular brand you use.The FDA has not reviewed this for! In inhibition of proliferation and induction of apoptosis in human esophageal cancer cell line ( HeLa ), one may! Organs that express the ligand CXCL12 for this receptor mediates homing of tumor cells to specific that! That has distinct potentials for use in anti-inflammation, chemoprevention, and for various types pain! Compared to the other components are all consumable to have a lot of space, or plan to them. Pages in category `` Zingiber zerumbet is widely distributed throughout the tropics, particularly Southeast! Growing from a forked ( sympodial ) underground, fleshy rhizome-stem soin capillaire shampooing! For them allow them to have a lot of space, or plan to manage them annually is native India... 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Be concluded that, potent antibacterial and antifungal phytochemicals are present in ethanol extract of zerumbet. Présent dans les sommités florales à maturité est excellent pour assouplir les cheveux ou bien rincé or may not to. The Polynesian canoe plants month with it being fine anti-diarrheal, de-wormer, and for types... Nurseries, too, base obtuse, apex acuminate, pubescent below ; to! 1991 ) Acetylated flavonol glycosides from Zingiber zerumbet is a species in the family Zingiberaceae, is perennial.

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