Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. That said, I was on Creon for about 18 months, if memory serves. What Are Side Effects of Creon? "Product Information. Scandipharm Inc, Birmingham, AL. The following are some of the side effects that are known to be associated with this medicine. Diarrhoea 3. If you experience drowsiness, dizziness, hypotension or a headache as side-effects when using Creon 10000 Capsule medicine then it may not be safe to drive a vehicle or operate heavy machinery.One should not drive a vehicle if using the medicine makes you drowsy, dizzy or lowers your blood-pressure extensively. I've been on Creon for almost 9 years, before my op, so therefore before becoming diabetic so don't know any difference. Creon 25000 Capsules - Patient Information Leaflet (PIL) by Mylan Creon capsules help most people whose bodies do not make enough enzymes to digest their food, but it may have unwanted side effects in a few people. This combination of enzymes is normally produced by the pancreas to help the body digest fat, protein, and sugars. Throw away any CREON that has been stored at these temperatures for more than 30 days. If you have severe or long-lasting abdominal pain, contact your doctor immediately. This eMedTV article presents more information on this medication, including who it is approved for, how to take it, possible side effects, and more. Although not all of these side effects may occur, if they do occur they may need medical attention. Bowel stricture formation occasionally occurred in children with cystic fibrosis who received high doses. Abdominal pain 2. Some side effects may occur that usually do not need medical attention. "Product Information. Along with its needed effects, pancrelipase (the active ingredient contained in Creon) may cause some unwanted effects. The most common side effects of pancrelipase include: diarrhea; upset stomach (indigestion) cough; Other possible side effects: Pancrelipase and other pancreatic enzyme products are made from the pancreas of pigs, the same pigs people eat as pork. What are the most common side effects with CREON? Nausea and vomiting 5. Creon Side Effects Diarrhea, constipation, headache, abdominal pain/cramps/bloating, gas, cough, nausea, or vomiting may occur. Scandipharm Inc, Birmingham, AL. If any of these effects persist … The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Find medication information including related drug classes, side effects, patient statistics and answers to … McNeil Pharmaceutical, Raritan, NJ. Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Creon capsules. Common Side Effects of Creon. All medicines can have side effects. [Ref], Common (1% to 10%): Blood cholesterol decreased, blood glucose increased, decreased appetite, diabetes mellitus, diabetes mellitus including subtypes, hyperglycemia, hypoglycemia, weight decreased, Frequency not reported: Hyperuricemia[Ref], Common (1% to 10%): ALT increased, AST increased, biliary tract stones, blood alkaline phosphatase increased, cholangitis, GGT increased, hydrocholecystis, Postmarketing reports: Asymptomatic liver enzyme elevations[Ref], Common (1% to 10%): Anemia, hematocrit, hemoglobin, red blood cell count, increased white blood cell count, Frequency not reported: Transient neutropenia with/without clinical sequelae[Ref], Common (1% to 10%): Bronchitis, cough, nasopharyngitis, oropharyngeal pain, respiratory tract infection, Common (1% to 10%): Asthenia, malaise, pain, pyrexia, Common (1% to 10%): Pruritus, rash, skin reactions, Frequency not reported: Itching, urticaria/hives, Postmarketing reports: Blotchy/red facial rash[Ref], Common (1% to 10%): Arthralgia, back pain, musculoskeletal pain, Postmarketing reports: Muscle spasm, myalgia[Ref], Common (1% to 10%): Contusion, hypertension, peripheral edema[Ref], Common (1% to 10%): Metastases to specific sites, recurrent pancreatic carcinoma, Postmarketing reports: Recurrence of preexisting carcinoma[Ref], Common (1% to 10%): Insomnia, irritability[Ref], A patient with a known history of allergy to another pancrelipase (the active ingredient contained in Creon) product developed a mild allergic reaction, including red, blotchy facial rash and itching. 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